AI-Powered Site Intelligence

Find the right sites,
faster — with AI.

LINEA's AI scores 250,000+ investigators against your protocol in real time. AcceleTrial manages every step from site selection to first patient enrolled.

See AcceleTrial Request Demo
01Site Intelligence

250,000+ records.
AI-scored against your protocol.

LINEA's AI scores every investigator record against your protocol parameters — therapeutic area, phase, indication, patient population — and surfaces your ranked site list in minutes, not weeks.

AcceleTrial® Site RankingsPhase III Oncology
1
Mayo Clinic, Rochester, MN
Oncology · High-volume research center
9.6
2
MD Anderson, Houston, TX
Oncology · High-volume research center
9.4
3
Memorial Sloan Kettering, NY
Oncology · Active research site
9.1
4
Dana-Farber, Boston, MA
Oncology · Active research site
8.9
5
UCSF Medical Center, SF, CA
Oncology · Active research site
8.7
02Activation

Up to 50% faster.
From AI ranking to first patient.

AcceleTrial converts your AI-ranked site list into a governed execution system — contracts, regulatory packages, SLA monitoring, and milestone tracking across your full site portfolio.

Site Activation Workflow12 sites
Protocol Defined & Sites Ranked
AcceleTrial scoring complete · 47 candidates
Day 1
Feasibility Outreach Sent
Automated questionnaires · Rapid multi-site outreach
Day 4
Contracts Under Review
12 sites selected · Budgets finalized
Day 18
Sites Activated
First patient enrolled
Day 34
03Research Site Index

The AI intelligence layer
behind every site decision

RSI continuously refreshes 250,000+ investigator records and scores them against protocol-specific criteria — so the site list AcceleTrial works from is always current, ranked, and verified.

Research Site Index: 250,000+ investigator records
Site / PIIndicationScoreActivity
Cleveland Clinic
Dr. B. Abadie
Cardiology
9.4
Johns Hopkins
Dr. E. Aldrich
Neurology
9.1
UCLA Medical
Dr. D. Bolos
Oncology
8.8
Emory University
Dr. K. Vanijcharoenkarn
Immunology
8.6
Scroll to explore
Platform Overview
250K+
Investigator Records
0
Countries Covered
Up to 50%
Faster Trial Start-up
0
Specialty Options
Recognized By
MD Tech Review for advancements in clinical study start-up technology, featuring a Q&A with Founder & President Kathleen Colatrella Read the feature →

AcceleTrial®

From AI-ranked sites
to first patient enrolled

AcceleTrial is the operating layer that runs after the AI scoring is done — governing every contract, document, milestone, and approval from site selection through activation.

Explore AcceleTrialRequest Demo
AcceleTrial: Site Score Breakdown
Population Fit
9.2
Experience Score
8.8
Operational Score
8.5
Diversity Score
9.4
Geographic Score
7.9
Protocol-Fit Score (0-10)9.1
AI-Powered Site Scoring

Every site AI-scored across seven protocol-specific dimensions: population fit, investigator experience, operational readiness, diversity, geographic coverage, enrollment reliability, and protocol compatibility.

Geographic Network Mapping

Visualize site density, competitive enrollment pressure, and patient population proximity across any indication and geography.

AI Enrollment Forecasting

AI-driven predictive modeling surfaces the sites most likely to meet your enrollment targets on time — scored against verified historical performance, not assumptions.

Investigator Intelligence

Complete profiles on every principal investigator: credentials, publication history, active trial load, and prior sponsor relationships.

Automated Feasibility at Scale

Digital questionnaires dispatched automatically, responses AI-scored against your protocol, and results ranked in the platform — replacing months of manual coordination.

Contract Milestone Tracking

Budgets, agreements, and startup milestones managed end-to-end across your entire site portfolio from one dashboard.

Research Site Index

The AI data layer
behind every site decision

The RSI combines 250,000+ verified investigator records with AI-powered protocol scoring — so AcceleTrial starts every engagement with a ranked, protocol-specific site list, not a generic database query.

250,000+ investigator records spanning 186 countries and 44,000+ distinct US institution labels
Monthly refresh with real-time updates on request, validation-backed source persistence, and quality controls
Protocol-aware scoring across population fit, experience, operations, diversity, and geography
12 supported UI languages for global sponsor and operations teams
Explore the RSI
250K+
Investigators
186
Countries
44K+
US Institutions
109
Specialties
96%
Sites Approved
12
UI Languages

How It Works

From protocol to first patient enrolled

1
Input Protocol

Enter therapeutic area, indication, phase, and enrollment targets. The AI scoring engine configures automatically.

2
AI Ranks Sites

LINEA's AI scores the full RSI against your protocol and returns a ranked, verified site list in minutes.

3
Automate Feasibility

Questionnaires go out automatically. AI scores responses against your protocol as they come in.

4
Activate Sites

Contracts, budgets, and regulatory milestones governed end-to-end through first patient enrolled.

Proven Results

What sponsors
achieve with LINEA

Up to 50%
Faster Trial Start-up

Faster trial start-up timeline when beginning with the right sites and protocol-aware activation workflow.

96%
Sites Approved and Included

Of targeted sites approved by the sponsor and ultimately included in a study, per the AcceleTrial fact sheet.

177
Patients Enrolled Early

One sponsor achieved 100% enrollment of 177 patients randomized, four months ahead of schedule.

250K+
Investigator Records

The current RSI parity-backed snapshot spans 186 countries, 109 specialties, and 44,000+ distinct US institution labels.

9
Specialist Sites in 4 Months

A rare disease sponsor activated 9 specialist sites in 4 months using AcceleTrial's targeted workflow.

109
Specialty Options

RSI exposes 109 normalized specialty options in the current runtime, covering virtually all therapeutic areas.

Customer Voices

What sponsors say
about working with LINEA

"

Our study reached 100% enrollment (177 patients randomized) four months ahead of schedule. LINEA's site insights and consistent follow-up were essential in filling recruitment gaps and driving this success. We are truly grateful for their collaboration.

Associate Director, Top 5 Pharma
"

I can't believe LINEA accomplished in 4 months what our CRO couldn't achieve in a year. With their support, we successfully activated 9 specialist sites for our rare disease neurotrophic keratitis trial. Their expertise and focus made all the difference.

Director of Operations, Biotech
"

LINEA has reliably delivered strong sites with credible feasibility to support our trials. They provide high-quality sites that have the expertise, experience, and patients to be successful in our trials.

Top 10 Pharma Company
"

We continually choose LINEA because of their differentiated site recruitment support.

Top 10 Pharma Company

About LINEA System

Turning fragmented work
into one operating system

Founded in 2008 by Kathleen Colatrella, LINEA System relaunched in 2018 as an AI-powered site selection and engagement platform. The goal: faster site activation and more reliable patient contribution with less site burden.

Data-Driven by Design
Every recommendation in AcceleTrial is grounded in verified site performance data, never assumptions.
Sponsor-First Focus
Built exclusively for sponsors and CROs. Our incentives are aligned with trial success, not site volume.
Continuous Verification
The RSI is not a static database. Every site is continuously evaluated against current enrollment and credentials.
Learn More About Us
LINEA System team
"The greatest opportunity to improve clinical trials is through site start-up. That is what LINEA was built to address."
Kathleen Colatrella, RPh, MS, Founder, LINEA System

Board of Advisors

Guided by industry leaders

Kathleen Colatrella
Kathleen Colatrella, RPh, MS
Founder

Founded LINEA System in 2008. Brings extensive drug development experience from running clinical trials at one of the world's largest pharmaceutical companies.

Laurie Myers
Laurie Myers
Board Advisor
COO, Cingulate Therapeutics

Senior clinical operations executive with extensive experience leading site networks and trial startup operations across multiple therapeutic areas.

Patrick Healy
Patrick Healy
Board Advisor
Co-Founder & President, Trial Runners

Co-founder of Trial Runners, a leading site management organization. Deep expertise in clinical site operations and sponsor-site relationships.

Faisal Alshalawi
Faisal Alshalawi
Board Advisor
Fund Manager, Alinma Investment Company

Fund manager with a focus on healthcare and technology investments. Brings strategic financial perspective to LINEA's growth and capital strategy.

View Full Leadership Page

AI Playbook & Resources

Intelligence for
modern trial sponsors

Playbook
The AI Site Selection Playbook for Clinical Sponsors

A practical framework for integrating AI tools into your site selection workflow, from protocol design through activation.

Read the Playbook
Guide
Why 70% of Site Selection Decisions Are Made on Bad Data

An examination of the data quality problem at the core of clinical site selection, and how verified databases change the equation.

Read the Guide
Case Study
How One Sponsor Reduced Site Startup Time by 38% in Phase III Oncology

How AcceleTrial's site scoring and automated feasibility workflows compressed a 14-week startup to just 9 weeks.

Read the Case Study

Get Started

When you begin with
the right sites, you reach patients faster.

See the platform in action. Explore RSI, AcceleTrial, and workflow intelligence built for sponsor and operations teams.

Request a Demo Explore the RSI